Exam Preview for 1606: Rethinking Asthma

Rethinking Asthma – Endotypes and Phenotypes

Please note: exam questions are subject to change.

1. Which of the following describes Asthma? Virus that triggers an inflammation of the bronchial tubes Heterogeneous disease – diverse in history, triggers, severity and responsiveness for every patient Hereditary disorder affecting the exocrine glands Infectious bacterial disease characterized by the growth of nodules (tubercles) in the tissues
2. Research finds that an Asthma diagnosis is often based on symptoms such as: Wheezing Shortness of breath Cough All of the above
3. A characteristic of the T2-High endotype, Basophil, includes: Blood-borne but activated in the tissues Does not respond to ICS therapy First line of defense Ingests invading microorganisms
4. In patients with late-onset Eosinophilic Asthma, a clinical consequence of T2-High phenotype is evidenced by: High blood and sputum eosinophilia Smooth muscle abnormalities Increases in total IgE Correlates with normal lung function
5. Which of the following biomarkers may be used to measure T2 High-Inflammation? Blood Sputum Cytometry Mannitol Challenge Test All of the above