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Assessment of Pulmonary Mechanics by Measuring Transpulmonary Pressure

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1.  Which of the following trans-pulmonary pressure calculations is incorrect?
  1. end-expiration PL = PEEP-Pes measured at end-expiration
  2. Lung Pplat = Pplat-Pes measured during end-inspiratory pause maneuver
  3. Lung Pdrive = (Pplat-Pes-end-inspiration) – (PEEP-Pes-end expiration)
  4. None of the above
2.  Which of the following is NOT true regarding esophageal balloon placement and common artifacts?
  1. The best esophageal balloon position for an average adult is ~30cm from the nares
  2. A kink in esophageal catheter will not show a pressure reading
  3. Esophageal spasm will show-up as a sustained pressure plateau
  4. The best esophageal balloon position for an average adult is ~45cm from the apex
3.  Pes measurements are influenced by all factors except for?
  1. Balloon placement
  2. Esophageal tone
  3. Ventilator inspiratory flow waveform
  4. Pleural Effusion
4.  Which combination of transpulmonary Pplat and Pdrive is considered safe?
  1. Pplat less than or equal to 30, Pdr less than or equal to 15
  2. Pplat less than or equal to 20, Pdr less than or equal to 10
  3. Pplat less than or equal to 32, less than or equal to 22
  4. None of the above are considered safe
5.  Which is correct about the EPVent-2 trial of PEEP set by transpulmonary pressure (Ptp)?
  1. Ptp guided PEEP reduced mortality by 15%
  2. Ptp guided PEEP increased mortality by 17%
  3. Mortality using Ptp guided PEEP the LOVS trial high PEEP were the same
  4. EPVent-2 trial did not use mortality as a study end-point

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